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Every point at which a section's wording changed, was added or was removed. Day-precise from 2017 (eCFR); before that, changes surface at the annual edition that first printed them (revised as of October 1). Current through Oct. 15, 2026.

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One email when a section of the FMCSRs is amended, added or removed, with the redline. The rules move about fifteen times a year, in clusters. No weekly filler.

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330 changes in 2023

December 28, 20232 sections

December 12, 20234 sections

December 8, 20231 section

November 27, 202318 sections

November 17, 202390 sections

November 16, 20232 sections

November 8, 20232 sections

October 13, 20234 sections

July 24, 20232 sections

  • amended§ 367.30Fees under the Unified Carrier Registration Plan and Agreement for Registration Year 2023.Part 367
  • amended§ 367.40Fees under the Unified Carrier Registration Plan and Agreement for Registration Years beginning in 2024 and each subsequent registration year thereafter.Part 367

June 22, 20232 sections

  • amended§ 367.30Fees under the Unified Carrier Registration Plan and Agreement for Registration Years Beginning in 2023 and Each Subsequent Registration Year Thereafter.Part 367
  • added§ 367.40xxxPart 367

June 1, 2023109 sections

  • amended§ 40.3What do the terms used in this part mean?Part 40
  • amended§ 40.13How do DOT drug and alcohol tests relate to non-DOT tests?Part 40
  • amended§ 40.14What collection information must employers provide to collectors?Part 40
  • amended§ 40.21May an employer stand down an employee before the MRO has completed the verification process?Part 40
  • amended§ 40.23What actions do employers take after receiving verified test results?Part 40
  • amended§ 40.25Must an employer check on the drug and alcohol testing record of employees it is intending to use to perform safety-sensitive duties?Part 40
  • amended§ 40.26What form must an employer use to report Management Information System (MIS) data to a DOT agency?Part 40
  • removed§ 40.29Where is other information on employer responsibilities found in this regulation?Part 40
  • amended§ 40.31Who may collect specimens for DOT drug testing?Part 40
  • amended§ 40.33What training requirements must a collector meet for urine collection?Part 40
  • amended§ 40.35What training requirements must a collector meet for oral fluid collection?Part 40
  • added§ 40.36What information about the DER must employers provide to collectors?Part 40
  • removed§ 40.37Where is other information on the role of collectors found in this regulation?Part 40
  • added§ 40.40What form is used to document a DOT collection?Part 40
  • amended§ 40.41May employers use the CCF for non-Federal collections or non-Federal forms for DOT collections?Part 40
  • added§ 40.42Where does a urine collection for a DOT drug test take place?Part 40
  • amended§ 40.43What steps must operators of collection sites and collectors take to protect the security and integrity of urine collections?Part 40
  • added§ 40.44What materials are used to collect urine specimens?Part 40
  • amended§ 40.45What materials are used to send urine specimens to the laboratory?Part 40
  • amended§ 40.47Where does an oral fluid collection for a DOT drug test take place?Part 40
  • added§ 40.48What steps must operators of collection sites and collectors take to protect the security and integrity of oral fluid collections?Part 40
  • amended§ 40.49What materials are used to collect oral fluid specimens?Part 40
  • amended§ 40.51What materials are used to send oral fluid specimens to the laboratory?Part 40
  • amended§ 40.61What are the preliminary steps in the drug testing collection process?Part 40
  • amended§ 40.63What steps does the collector take in the collection process before the employee provides a urine specimen?Part 40
  • amended§ 40.65What does the collector check for when the employee presents a urine specimen?Part 40
  • amended§ 40.67When and how is a directly observed urine collection conducted?Part 40
  • amended§ 40.69How is a monitored urine collection conducted?Part 40
  • amended§ 40.71How does the collector prepare the urine specimen?Part 40
  • added§ 40.72What steps does the collector take in the collection process before the employee provides an oral fluid specimen?Part 40
  • amended§ 40.73How is an oral fluid specimen collected?Part 40
  • added§ 40.74How does the collector prepare the oral fluid specimens?Part 40
  • added§ 40.75-40.78[Reserved]Part 40
  • added§ 40.79How is the collection process completed?Part 40
  • amended§ 40.81What laboratories may be used for DOT drug testing?Part 40
  • added§ 40.82What drugs do laboratories test for?Part 40
  • amended§ 40.83How do laboratories process incoming specimens?Part 40
  • added§ 40.84How long does the laboratory retain specimens after testing?Part 40
  • amended§ 40.85What are the cutoff concentrations for urine drug tests?Part 40
  • added§ 40.86What is urine validity testing, and are laboratories required to conduct it?Part 40
  • amended§ 40.87What validity tests must laboratories conduct on primary urine specimens?Part 40
  • added§ 40.88What criteria do laboratories use to establish that a urine specimen is dilute or substituted?Part 40
  • amended§ 40.89What are the adulterant cutoff concentrations for initial and confirmation urine tests?Part 40
  • added§ 40.90What criteria do laboratories use to establish that a urine specimen is invalid?Part 40
  • amended§ 40.91What are the cutoff concentrations for oral fluid drug tests?Part 40
  • added§ 40.92What is oral fluid validity testing, and are laboratories required to conduct it?Part 40
  • amended§ 40.93What validity tests must laboratories conduct on primary oral fluid specimens?Part 40
  • removed§ 40.95What are the adulterant cutoff concentrations for initial and confirmation tests?Part 40
  • removed§ 40.96What criteria do laboratories use to establish that a specimen is invalid?Part 40
  • amended§ 40.97What do laboratories report and how do they report it?Part 40
  • removed§ 40.99How long does the laboratory retain specimens after testing?Part 40
  • amended§ 40.111When and how must a laboratory disclose statistical summaries and other information it maintains?Part 40
  • amended§ 40.121Who is qualified to act as an MRO?Part 40
  • amended§ 40.123What are the MRO's responsibilities in the DOT drug testing program?Part 40
  • amended§ 40.127What are the MRO's functions in reviewing negative test results?Part 40
  • amended§ 40.129What are the MRO's functions in reviewing laboratory confirmed non-negative drug test results?Part 40
  • amended§ 40.135What does the MRO tell the employee at the beginning of the verification interview?Part 40
  • amended§ 40.139On what basis does the MRO verify test results involving 6-acetylmorphine, codeine, and morphine?Part 40
  • amended§ 40.141How does the MRO obtain information for the verification decision?Part 40
  • amended§ 40.145On what basis does the MRO verify test results involving adulteration or substitution?Part 40
  • amended§ 40.151What are MROs prohibited from doing as part of the verification process?Part 40
  • amended§ 40.159What does the MRO do when a drug test result is invalid?Part 40
  • amended§ 40.161What does the MRO do when a drug test specimen is rejected for testing?Part 40
  • amended§ 40.163How does the MRO report drug test results?Part 40
  • amended§ 40.177What does the second laboratory do with the split specimen when it is tested to reconfirm the presence of a drug or drug metabolite?Part 40
  • amended§ 40.179What does the second laboratory do with the split specimen when it is tested to reconfirm an adulterated test result?Part 40
  • amended§ 40.181What does the second laboratory do with the split specimen when it is tested to reconfirm a substituted test result?Part 40
  • amended§ 40.187What does the MRO do with split specimen laboratory results?Part 40
  • amended§ 40.191What is a refusal to take a DOT drug test, and what are the consequences?Part 40
  • amended§ 40.193What happens when an employee does not provide a sufficient amount of specimen for a drug test?Part 40
  • amended§ 40.195What happens when an individual is unable to provide a sufficient amount of specimen for a pre-employment, follow-up, or return-to-duty test because of a permanent or long-term medical condition?Part 40
  • amended§ 40.197What happens when an employer receives a report of a dilute urine specimen?Part 40
  • amended§ 40.199What problems always cause a drug test to be cancelled?Part 40
  • amended§ 40.201What problems always cause a drug test to be cancelled and may result in a requirement for another collection?Part 40
  • amended§ 40.207What is the effect of a cancelled drug test?Part 40
  • amended§ 40.208What problems require corrective action but do not result in the cancellation of a test?Part 40
  • amended§ 40.209What procedural problems do not result in the cancellation of a test and do not require correction?Part 40
  • amended§ 40.210What kinds of drug tests are permitted under the regulations?Part 40
  • amended§ 40.225What form is used for an alcohol test?Part 40
  • amended§ 40.261What is a refusal to take an alcohol test, and what are the consequences?Part 40
  • amended§ 40.281Who is qualified to act as a SAP?Part 40
  • amended§ 40.283How does a certification organization obtain recognition for its members as SAPs?Part 40
  • amended§ 40.285When is a SAP evaluation required?Part 40
  • amended§ 40.291What is the role of the SAP in the evaluation, referral, and treatment process of an employee who has violated DOT agency drug and alcohol testing regulations?Part 40
  • amended§ 40.293What is the SAP's function in conducting the initial evaluation of an employee?Part 40
  • amended§ 40.297Does anyone have the authority to change a SAP's initial evaluation?Part 40
  • amended§ 40.301What is the SAP's function in the follow-up evaluation of an employee?Part 40
  • amended§ 40.305How does the return-to-duty process conclude?Part 40
  • amended§ 40.307What is the SAP's function in prescribing the employee's follow-up tests?Part 40
  • amended§ 40.311What are the requirements concerning SAP reports?Part 40
  • amended§ 40.327When must the MRO report medical information gathered in the verification process?Part 40
  • amended§ 40.345In what circumstances may a C/TPA act as an intermediary in the transmission of drug and alcohol testing information to employers?Part 40
  • amended§ 40.355What limitations apply to the activities of service agents?Part 40
  • amended§ 40.365What is the Department's policy concerning starting a PIE proceeding?Part 40
  • amendedAppendix B to Part 40Appendix B to Part 40—Oral Fluid Collection Kit ContentsPart 40
  • removedAppendix C to Part 40Appendix C to Part 40—DOT Drug-Testing Semi-Annual Laboratory Report to DOTPart 40
  • addedAppendix C to Part 40 [Reserved]Appendix C to Part 40 [Reserved]Part 40
  • amendedAppendix D to Part 40Appendix D to Part 40—DOT Drug Testing Semi-Annual Laboratory Report to EmployersPart 40
  • amendedAppendix E to Part 40Appendix E to Part 40—Drug Testing Semi-Annual Laboratory Report to DOTPart 40
  • amendedAppendix F to Part 40Appendix F to Part 40—Report Format: Split Specimen Failure To ReconfirmPart 40
  • amendedAppendix G to Part 40Appendix G to Part 40—SAP Equivalency Requirements for Certification OrganizationsPart 40
  • amendedAppendix H to Part 40Appendix H to Part 40—Drug and Alcohol Testing Information that C/TPAs May Transmit to EmployersPart 40
  • addedAppendix I to Part 40Appendix I to Part 40—Alcohol Testing FormPart 40
  • addedAppendix J to Part 40Appendix J to Part 40—DOT Drug and Alcohol Testing Management Information System (MIS) Data Collection FormPart 40
  • amended§ 382.107Definitions.Part 382
  • amended§ 382.401Retention of records.Part 382
  • amended§ 382.403Reporting of results in a management information system.Part 382
  • amended§ 382.409Medical review officer or consortium/third party administrator record retention for controlled substances.Part 382
  • amended§ 382.705Reporting to the Clearinghouse.Part 382

May 2, 202391 sections

  • amended§ 40.3What do the terms used in this part mean?Part 40
  • amended§ 40.13How do DOT drug and alcohol tests relate to non-DOT tests?Part 40
  • amended§ 40.14What collection information must employers provide to collectors?Part 40
  • amended§ 40.21May an employer stand down an employee before the MRO has completed the verification process?Part 40
  • amended§ 40.23What actions do employers take after receiving verified test results?Part 40
  • amended§ 40.25Must an employer check on the drug and alcohol testing record of employees it is intending to use to perform safety-sensitive duties?Part 40
  • amended§ 40.26What form must an employer use to report Management Information System (MIS) data to a DOT agency?Part 40
  • amended§ 40.29Where is other information on employer responsibilities found in this regulation?Part 40
  • amended§ 40.31Who may collect urine specimens for DOT drug testing?Part 40
  • amended§ 40.33What training requirements must a collector meet?Part 40
  • amended§ 40.35What information about the DER must employers provide to collectors?Part 40
  • amended§ 40.37Where is other information on the role of collectors found in this regulation?Part 40
  • amended§ 40.41Where does a urine collection for a DOT drug test take place?Part 40
  • amended§ 40.43What steps must operators of collection sites take to protect the security and integrity of urine collections?Part 40
  • amended§ 40.45What form is used to document a DOT urine collection?Part 40
  • amended§ 40.47May employers use the CCF for non-Federal collections or non-Federal forms for DOT collections?Part 40
  • amended§ 40.49What materials are used to collect urine specimens?Part 40
  • amended§ 40.51What materials are used to send urine specimens to the laboratory?Part 40
  • amended§ 40.61What are the preliminary steps in the collection process?Part 40
  • amended§ 40.63What steps does the collector take in the collection process before the employee provides a urine specimen?Part 40
  • amended§ 40.65What does the collector check for when the employee presents a specimen?Part 40
  • amended§ 40.67When and how is a directly observed collection conducted?Part 40
  • amended§ 40.69How is a monitored collection conducted?Part 40
  • amended§ 40.71How does the collector prepare the specimens?Part 40
  • amended§ 40.73How is the collection process completed?Part 40
  • amended§ 40.81What laboratories may be used for DOT drug testing?Part 40
  • amended§ 40.83How do laboratories process incoming specimens?Part 40
  • amended§ 40.85What drugs do laboratories test for?Part 40
  • amended§ 40.87What are the cutoff concentrations for drug tests?Part 40
  • amended§ 40.89What is validity testing, and are laboratories required to conduct it?Part 40
  • amended§ 40.91What validity tests must laboratories conduct on primary specimens?Part 40
  • amended§ 40.93What criteria do laboratories use to establish that a specimen is dilute or substituted?Part 40
  • amended§ 40.95What are the adulterant cutoff concentrations for initial and confirmation tests?Part 40
  • amended§ 40.96What criteria do laboratories use to establish that a specimen is invalid?Part 40
  • amended§ 40.97What do laboratories report and how do they report it?Part 40
  • amended§ 40.99How long does the laboratory retain specimens after testing?Part 40
  • amended§ 40.111When and how must a laboratory disclose statistical summaries and other information it maintains?Part 40
  • amended§ 40.121Who is qualified to act as an MRO?Part 40
  • amended§ 40.123What are the MRO's responsibilities in the DOT drug testing program?Part 40
  • amended§ 40.127What are the MRO's functions in reviewing negative test results?Part 40
  • amended§ 40.129What are the MRO's functions in reviewing laboratory confirmed non-negative drug test results?Part 40
  • amended§ 40.135What does the MRO tell the employee at the beginning of the verification interview?Part 40
  • amended§ 40.139On what basis does the MRO verify test results involving 6-acetylmorphine, codeine, and morphine?Part 40
  • amended§ 40.141How does the MRO obtain information for the verification decision?Part 40
  • amended§ 40.145On what basis does the MRO verify test results involving adulteration or substitution?Part 40
  • amended§ 40.151What are MROs prohibited from doing as part of the verification process?Part 40
  • amended§ 40.159What does the MRO do when a drug test result is invalid?Part 40
  • amended§ 40.161What does the MRO do when a drug test specimen is rejected for testing?Part 40
  • amended§ 40.163How does the MRO report drug test results?Part 40
  • amended§ 40.177What does the second laboratory do with the split specimen when it is tested to reconfirm the presence of a drug or drug metabolite?Part 40
  • amended§ 40.179What does the second laboratory do with the split specimen when it is tested to reconfirm an adulterated test result?Part 40
  • amended§ 40.181What does the second laboratory do with the split specimen when it is tested to reconfirm a substituted test result?Part 40
  • amended§ 40.187What does the MRO do with split specimen laboratory results?Part 40
  • amended§ 40.191What is a refusal to take a DOT drug test, and what are the consequences?Part 40
  • amended§ 40.193What happens when an employee does not provide a sufficient amount of urine for a drug test?Part 40
  • amended§ 40.195What happens when an individual is unable to provide a sufficient amount of urine for a pre-employment follow-up or return-to-duty test because of a permanent or long-term medical condition?Part 40
  • amended§ 40.197What happens when an employer receives a report of a dilute specimen?Part 40
  • amended§ 40.199What problems always cause a drug test to be cancelled?Part 40
  • amended§ 40.201What problems always cause a drug test to be cancelled and may result in a requirement for another collection?Part 40
  • amended§ 40.207What is the effect of a cancelled drug test?Part 40
  • amended§ 40.208What problem requires corrective action but does not result in the cancellation of a test?Part 40
  • amended§ 40.209What procedural problems do not result in the cancellation of a test and do not require correction?Part 40
  • amended§ 40.210Are drug tests other than urine permitted under the regulations?Part 40
  • amended§ 40.225What form is used for an alcohol test?Part 40
  • amended§ 40.261What is a refusal to take an alcohol test, and what are the consequences?Part 40
  • amended§ 40.281Who is qualified to act as a SAP?Part 40
  • amended§ 40.283How does a certification organization obtain recognition for its members as SAPs?Part 40
  • amended§ 40.285When is a SAP evaluation required?Part 40
  • amended§ 40.291What is the role of the SAP in the evaluation, referral, and treatment process of an employee who has violated DOT agency drug and alcohol testing regulations?Part 40
  • amended§ 40.293What is the SAP's function in conducting the initial evaluation of an employee?Part 40
  • amended§ 40.297Does anyone have the authority to change a SAP's initial evaluation?Part 40
  • amended§ 40.301What is the SAP's function in the follow-up evaluation of an employee?Part 40
  • amended§ 40.305How does the return-to-duty process conclude?Part 40
  • amended§ 40.307What is the SAP's function in prescribing the employee's follow-up tests?Part 40
  • amended§ 40.311What are the requirements concerning SAP reports?Part 40
  • amended§ 40.327When must the MRO report medical information gathered in the verification process?Part 40
  • amended§ 40.345In what circumstances may a C/TPA act as an intermediary in the transmission of drug and alcohol testing information to employers?Part 40
  • amended§ 40.355What limitations apply to the activities of service agents?Part 40
  • amended§ 40.365What is the Department's policy concerning starting a PIE proceeding?Part 40
  • amendedAppendix B to Part 40Appendix B to Part 40—DOT Drug-Testing Semi-Annual Laboratory Report to EmployersPart 40
  • amendedAppendix C to Part 40Appendix C to Part 40—DOT Drug-Testing Semi-Annual Laboratory Report to DOTPart 40
  • amendedAppendix D to Part 40Appendix D to Part 40—Report Format: Split Specimen Failure To ReconfirmPart 40
  • amendedAppendix E to Part 40Appendix E to Part 40—SAP Equivalency Requirements for Certification OrganizationsPart 40
  • amendedAppendix F to Part 40Appendix F to Part 40—Drug and Alcohol Testing Information that C/TPAs May Transmit to EmployersPart 40
  • amendedAppendix G to Part 40Appendix G to Part 40—Alcohol Testing FormPart 40
  • amendedAppendix H to Part 40Appendix H to Part 40—DOT Drug and Alcohol Testing Management Information System (MIS) Data Collection FormPart 40
  • amended§ 382.107Definitions.Part 382
  • amended§ 382.401Retention of records.Part 382
  • amended§ 382.403Reporting of results in a management information system.Part 382
  • amended§ 382.409Medical review officer or consortium/third party administrator record retention for controlled substances.Part 382
  • amended§ 382.705Reporting to the Clearinghouse.Part 382

January 23, 20231 section

January 6, 20232 sections